Cardinals-Twins opener tests bats with IL-heavy lineups

Cardinals vs. – On June 12, 2026, the St. Louis Cardinals visit the Minnesota Twins at 8:10 p.m. ET at Target Field, with Joe Ryan starting for Minnesota and Kyle Leahy for St. Louis. Alec Burleson enters with a three-game homer streak, while both teams bring multiple injurie
By the time the first pitch window opened on Friday night, it was already clear this wasn’t going to be a simple matchup on paper. The St. Louis Cardinals are in Minnesota for a game at Target Field at 8:10 p.m. ET, and the lineup picture comes with a long list of names on the injured list.
The Cardinals are 37-29 and second in the NL Central. The Twins are 31-39 and third in the AL Central. Minnesota will hand the ball to Joe Ryan, who is 4-3 with a 3.07 ERA. St. Louis counters with Kyle Leahy, who is 5-3 with a 4.42 ERA.
St. Louis’ Alec Burleson arrives with a three-game homer streak, carrying into this one the kind of momentum that can swing a game quickly—especially when both teams are also dealing with missing pieces.
How to watch St. Louis Cardinals vs. Minnesota Twins
The game is scheduled for 8:10 p.m. ET on Friday, June 12, 2026, at Target Field.
Cardinals vs. Twins odds
Odds are provided by BetMGM.
Injury reports
The Twins have a crowded injury list. Ryan Jeffers is on the 10 Day IL (Hand). Bailey Ober is on the 15 Day IL (Elbow). Cole Sands is on the 15 Day IL (Forearm). Mick Abel is on the 15 Day IL (Elbow). Kendry Rojas is on the 15 Day IL (Elbow). Pablo Lopez is on the 60 Day IL (Elbow). Garrett Acton is on the 60 Day IL (Shoulder). David Festa is on the 60 Day IL (Shoulder).
For the Cardinals, Ryan Fernandez is on the 15 Day IL (Back). Ramón Urías is on the 60 Day IL (Elbow).
Stats to know
Minnesota’s Byron Buxton has been a force this season. He has hit 20 home runs, ranking 3rd in MLB. He has also tallied 32 RBIs and scored 43 runs. In 261 plate appearances, Buxton is hitting .256 with a .318 OBP and .559 SLG. His walk rate is 7.3%, and his strikeout rate is 26.1%. On the base paths, he has six steals on six attempts.
Brooks Lee’s season line adds another layer to the Twins’ profile: in 261 plate appearances, he has slashed .238/.296/.410. He has hit 10 long balls and driven in 38 runs, with a strikeout rate of 17.2% and a walk rate of 6.9%. Lee has also come around to score 29 times.
Jordan Walker brings his own power and production for St. Louis. He is hitting .302 with a .358 OBP and .561 SLG. His strikeout rate is 25.4% and his walk rate is 7.5%. Walker’s OPS is .919, which ranks 11th in MLB, and he has scored 45 runs. In 279 plate appearances, he has hit 17 home runs (9th in MLB) and driven in 52 runs (2nd in MLB). Walker has recorded 10 steals on 13 attempts.
Alec Burleson’s numbers round out the Cardinals’ current scoring picture. In 284 plate appearances, he has slashed .290/.356/.486. He has hit 11 long balls and driven in 48 runs (7th in MLB), with a strikeout rate of 15.1% and a walk rate of 8.8%. He has scored 35 runs.
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Cardinals vs Twins June 12 2026 Joe Ryan Kyle Leahy Alec Burleson Byron Buxton Target Field MLB odds BetMGM