Cardinals 2026 – Arizona’s 2026 schedule already looked punishing, and the betting lines made it even clearer, with most games priced as double-digit underdog spots.
For the Arizona Cardinals, the road to 2026 was always going to be long.. The matchups are built in—three of the best teams in the entire league twice each through NFC West membership. plus full slates against the AFC West and the NFC East.. When the full schedule finally landed, the bleak picture only sharpened.
The Cardinals’ year is now mapped out week by week, and the current betting spreads, shared via DraftKings, leave them staring at a tough reality. In eight games, Arizona is listed as a double-digit underdog. Even when the gap isn’t as large, the list still reads like an obstacle course.
The toughest stretches start immediately.. Arizona opens at the Chargers (-11.5) before heading into a Week 2 home matchup against the Seahawks (-10).. By Week 3, the Cardinals are at the 49ers (-11.5), then they’re still catching points at the Giants (-7).. The Lions come next in Week 5. with Arizona down at least eight points (-8.5). and the punishment keeps rolling at the Rams (-13.5) in Week 6.
There are a few weeks where the margins look slightly less brutal. but “winnable” doesn’t really enter the conversation for long.. The Cardinals are at the Broncos (-7.5) in Week 7, then at the Cowboys (-10.5) in Week 8.. Week 10 brings another difficult draw at the Rams (-10.5) after Week 9 at the Seahawks (-13.5).. Even the Chiefs visit comes with a steep price, as Arizona is at Chiefs (-11.5) in Week 11.
After all that, there’s at least a small pocket of relief—though it arrives late.. Following a Week 14 bye, Arizona has a cluster of games that are priced closer to coin-flip territory.. Week 15 features the Jets (-1.5), and then the Cardinals head to the Saints (-5.5) in Week 16.. They wrap the season at home against the Raiders (-1.5) in Week 17. before closing with a tough finish at the 49ers (-8.5) in Week 18.
Between those comparatively reachable dates are still plenty of heavy hurdles: the Commanders are favored (-4.5) in Week 12, and the Eagles come next (-8.5) in Week 13.
Put simply, Arizona’s schedule doesn’t offer many easy answers, and the spreads reflect that. By the time the Cardinals reach that very late Week 14 bye, the season could be steering toward full-blown tank mode—if the early results match the numbers.
Arizona Cardinals 2026 NFL schedule DraftKings spreads NFL betting lines NFC West Chargers Seahawks 49ers Rams Chiefs