2 dead after fiery I-81 crash triggers oxygen tank explosion in Frederick County
FREDERICK COUNTY, Va. (7News) — A chaotic crash with fire, exploding oxygen tanks and a billowing cloud of black smoke left two people dead on Interstate 81 in Frederick County Thursday night.
It all started around 8:17 p.m. when a car didn’t yield while trying to get on I-81 southbound from the ramp, Virginia State Police said.
A semi then slammed into the car before driving straight through the median and hitting a northbound truck that was carrying oxygen tanks. The crash led to a fire and the oxygen tanks exploded.
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Photos and videos sent to 7News showed the massive smoke cloud that erupted moments after it happened. State police said the explosion also damaged a Frederick County sheriff’s vehicle.
Two people were killed in a multi-vehicle crash that ended with an explosion on I-81 in Frederick County, Virginia, on Sept. 10, 2026. (Rachel Smith/Chime In)
The semi driver died at the scene. The driver of the oxygen tank truck was rushed to the hospital, but later died as well.
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The driver of the passenger car was not injured and will face charges.
The investigation is ongoing.